Closing the Women’s Health Gap

Despite living longer than men, women spend a quarter of their lives in worse health, prompting the World Economic Forum and the McKinsey Health Institute to publish an in-depth report to unpack the underlying factors driving the disparity.

The report explores the root causes of the women’s health gap, which span far beyond sexual and reproductive health even though the area is a go-to oversimplification for many gender differences. (Chart: Contributing Factors to Women’s Health Burden)

  • Just 5% of women’s health burden is related to gender-specific conditions (maternal and gynecological)
  • 47% stems from conditions that affect women either disproportionately (depression, auto-immune disease) or differently (AFib, colon cancer)
  • 43% comes from conditions that don’t affect women disproportionately or differently (ischemic heart disease, tuberculosis, etc.)

The large disparity resulting from conditions that impact everyone more-or-less equally can be attributed to several systemic issues, which the report does a great job outlining alongside possible solutions.

  • Better clinical trial design is needed to ensure equitable representation for conditions that affect women differently, such as incorporating male vs. female disease prevalence mix and using sex-specific thresholds for biomarkers.
  • Accurately assessing the prevalence of conditions such as endometriosis and menopause is needed to improve the notoriously underestimated metrics, which leads to underinvestment due to misunderstood market potential. 
  • Enhancing access to gender-specific care is critical to improving outcomes, which might include health systems implementing new guidelines (e.g, sex-specific cutoffs for biomarkers, discharge checklists) to guide decision making and minimize biases.

In typical McKinsey fashion, the report devotes significant real estate to the economic burden of the women’s health gap, which if closed could boost global GDP by $1T due to improved workforce participation. It’s also worth noting that 10 conditions contribute over half of the economic burden. (Chart: Economic Burden by Condition)

The Takeaway

Tackling the women’s health gap is essential for far better reasons than boosting GDP, but regardless of the justification, progress depends on addressing the issues outlined in this report. Glaring research gaps, disparities in care delivery, and underinvestment have led to massive disparities in women’s health, but they’ve also created a huge opportunity for those that can help to solve them.

FemTec Health Emerges From Stealth, Acquires Birchbox

Former Livongo executive Dr. Kimon Angelides announced that FemTec Health, a technology-focused women’s health sciences company, is emerging from stealth with $38m in funding and the acquisition of subscription box pioneer Birchbox.

FemTec was originally formed in May 2020 with the aim of using technology to personalize care for women across the health continuum, from specialty and reproductive care to mental health and chronic condition management.

  • At launch, FemTec has over 10m members, two in-progress clinical trials, and 150 employees. Using a combination of AI and predictive analytics, it is looking to create a unified experience for its products and services across multiple channels, including D2C, B2B (employers, health plans), and subscriptions.
  • BiomeAI is the data analytics platform around which most of FemTec’s solutions revolve, which customizes care by using machine learning to transform data (consumer, genetic, microbiome, biometric) into personalized product and treatment recommendations.
  • Key acquisitions have helped FemTec launch with an established member base, such as digital cosmetics store Mira Beauty, social marketing platform Liquid Grid, and beauty box early mover Birchbox. FemTec announced plans to re-launch Birchbox later this year with a focus on BiomeAI-curated skin and healthcare products as opposed to beauty supplies.

The Takeaway

While FemTec is first and foremost a female health company, its acquisition history and BiomeAI recommendation platform show that it will likely focus more on consumer products than other competitors in the space. Female health is a giant market and one that’s been historically underserved, opening up plenty of runway for FemTec to meet unmet demand for personalized care.

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