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UpToDate Expert AI, Healthcare 2030, and What Are Doctors For?
September 25, 2025
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Together with
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“Surveys have suggested that many people are more confident in AI diagnoses than in those rendered by professionals. Meanwhile, in the United States alone, misdiagnosis disables hundreds of thousands of people each year; autopsy studies suggest that it contributes to perhaps one in every ten deaths.”
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Weill Cornell Medicine Physician Dr. Dhruv Khullar
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ICYMI: Digital Health Wire is launching a new series to profile the players taking clinical AI from promise to practice, and we couldn’t have asked for a better debut spotlight than Amigo. Healthcare has high stakes, high variance, and high skepticism – a holy trinity of AI resistance that clinicians won’t overcome through a leap of faith. Amigo is giving providers the infrastructure to build AI agents they can genuinely trust, and we’re excited to share an inside look at the process and platform that makes it possible.
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Right when you think Wolters Kluwer might just let everyone else have all the AI fun, it debuted UpToDate Expert AI to give the world’s most widely used clinical decision support tool a much-needed AI overhaul.
Wolters Kluwer took its time with the launch. The incumbent CDS juggernaut is used by 3M doctors worldwide, so it had plenty of users to disappoint with a hasty roll out.
- That said, nimble competition has been gaining ground pretty much as fast as it takes to download OpenEvidence from the App Store.
- The good news is that WK made the most of the extra development time.
Here’s what sets UpToDate Expert AI apart. Unlike general-purpose chatbots, the AI-enhanced version of UpToDate is built exclusively on WK’s peer-reviewed content library.
- It draws on 30+ years of evidence-based research authored by 7,600 experts, rather than the open web or selective journals.
- That allows it to quickly answer complex clinical questions, while surfacing all of its sources, assumptions, and step-by-step reasoning directly in the response. Probably safe to assume that also helps with hallucinations.
- Those answers still manage to be easy to scan at the bedside and will look extremely familiar to any doctor that’s ever read an UpToDate article (or one that’s been reading them for a decade).
The extra time in the oven means that more features are baked in. Wolters Kluwer knows its audience, and UpToDate Expert AI’s biggest leg up on the competition is its fine-tuning for health systems.
- Enterprise-grade governance, compliance, and workflow integration are all standard out-of-the-box, giving UpToDate Expert AI an advantage for a system-wide implementation over OpenEvidence or Doximity.
The Takeaway
It turns out that the 800-pound clinical support gorilla wasn’t going to let the newcomers eat its lunch forever, and UpToDate Expert AI gives health systems plenty of reasons to keep rolling with Wolters Kluwer.
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Under the Hood of Navina’s AI
Navina’s AI engine harnesses over 600 proprietary algorithms to transform fragmented patient data into actionable clinical intelligence at the point of care. It’s shaped with the expertise of physicians to turn multiple data sources (EHR, HIE, claims, care gap files, etc.) into contextualized insights like suspected conditions or evidence for care gap closures – each linked back to the original source. Download the whitepaper to see examples of Navina’s AI in action.
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Next Generation Ambient Tech and Agents
The ambient AI transformation is already sweeping across health systems, reducing administrative burdens and improving patient outcomes. So, what’s next? Tune into this on-demand session to learn how systems like Carle Health and Denver Health are leveraging Nabla to eliminate Pajama Time and build a future where agentic AI unlocks true workforce sustainability.
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- Glooko Acquires Monarch: Diabetes management company Glooko acquired Monarch Medical Technologies, the developer of the popular EndoTool inpatient insulin dosing system. The move makes Glooko perhaps the only diabetes management company with an integrated platform able to support patients across the full continuum of care from the hospital to specialty care to the home. Integrating the EndoTool with Glooko’s outpatient platform will help ensure smoother transitions and post-discharge monitoring – not a bad way to put a $100M Series F to good use.
- What Are Doctors For? A thought-provoking article in The New Yorker explored the transforming role of doctors in a world where AI alone can diagnose patients. That world looks like it’s quickly approaching, and the author does a great job articulating the differences between diagnosing people and competently caring for them. “Just because you have a Japanese-English dictionary on your desk doesn’t mean you’re fluent in Japanese.” One seemingly AI-proof aspect of a doctor’s role that wasn’t mentioned: liability.
- Inbox Closes $20M: Inbox Health hauled in $20M of growth funding to accelerate its AI for patient billing. Patient A/R is one of the fastest growing problems in healthcare, and Inbox is leveraging AI agents to modernize the entire experience from billing and collections to payments and support. The automations reportedly allow 90% of payments to be collected within the first 15 days of receiving a bill.
- DiMe Healthcare 2030: DiMe just wrapped the first Healthcare 2030 Summit with the release of its aptly named blueprint for guiding innovation in the years ahead, Healthcare 2030: An Impact Thesis for the Digital Era of Medicine. The thesis serves as a practical roadmap for navigating the twin pressures reshaping U.S. healthcare: severe economic headwinds and unprecedented technological innovation. Check out the full thesis for a stellar breakdown of the four impact areas to pursue through 2030 (prevention, personalization, outcomes, sustainability), as well as the technical drivers behind them (data, compute, connectivity, communication).
- WISeR WORRIeS: Providers are pushing back against CMS’ new WISeR model that aims to reduce unnecessary spending in traditional Medicare by requiring AI-powered prior authorizations for “low value” services – which apparently cost Medicare $5.8B in 2022. The WISeR pilot impacting six states has already prompted Democratic lawmakers to send at least two letters urging CMS to halt the program due to concerns over an AI-flurry of care denials that might reduce quality, increase administrative burdens on providers, and “open the door to further erosion of our Medicare system.”
- PE Hits the ED: A new study in the Annals of Internal Medicine uncovered a spike in patient deaths in the ED after hospitals get acquired by private equity. Researchers compared data from 49 PE-owned hospitals to 293 matched controls from 2009 to 2019, which showed that ED deaths climbed 13% from a baseline of 52 deaths / 10k visits following a PE acquisition. It doesn’t seem too far-fetched to link the extra deaths to the fact that PE firms reduced full-time employees by an average of 11.6% and slashed salaries in the ED by 18%.
- Medline Brings on Providence & Northwestern: Healthcare supply chain giant Medline is bringing on Providence and Northwestern Medicine to help steer the design of Mpower, an upcoming AI-powered “digital control tower” for hospital logistics. Mpower is built on Microsoft Azure AI to deliver proactive insights that streamline inventory and ensure supply chain resiliency. Both health systems will pilot the new tool ahead of its release in early 2026.
- UnitedHealthcare Goes DTC: UnitedHealthcare unveiled a new direct-to-consumer digital shopping experience dubbed UHC Store. Over 6M eligible commercial members can now access the UHC Store to complement their benefits at any time throughout the year with discounted health and wellness offerings at no cost to their employers. At launch, that includes programs for women’s health and mental health, family planning and pregnancy, fitness and nutrition, as well as health coordination resources for chronic conditions like diabetes.
- AI Industry Cozy With Providers: A new study in JAMA tracks the medical AI industry’s payments to healthcare providers and hospitals, which totaled $120M from 2017 to 2023. Cardiologists topped the charts by raking in $59M, while radiologists ranked second at $40M despite 77% of FDA authorizations for AI-enabled devices belonging to radiology. The research highlights important issues around conflicts of interest for physicians and adequate disclosures from the medical AI industry.
- FlyteHealth + Heartbeat: FlyteHealth and Heartbeat Health are joining forces to deliver an integrated virtual cardiometabolic and cardiology care program. The combined solution addresses conditions from pre-diabetes and hypertension to cardiovascular disease through a single entry point for payors and employers. Features include AI-driven care plans, multidisciplinary teams, remote monitoring, and patient-facing mobile apps geared toward eliminating care gaps and improving overall outcomes.
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10 Strategies to Expedite Provider Credentialing
Lagging provider credentialing workflows can create a wave of unexpected care delays and financial setbacks. Sidestep these pitfalls by tuning into Medallion’s recording of 10 Key Strategies to Expedite Provider Credentialing and see how your organization can keep a well-oiled team and patient care intact through the ever-evolving changes seen in healthcare.
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Achieve Ambient AI Scale With Abridge
According to a new report from MIT, 95% of generative AI implementations fail. At Abridge, we have helped 150+ health systems scale ambient AI to tens of thousands of clinicians—many in a matter of weeks. For the first time ever, we are sharing those steep adoption curves at partners, along with impact metrics and testimonials from 19 health systems. If your ambient AI implementation isn’t scaling at speed, Abridge can help.
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- Start Getting Leads From ChatGPT and Google AI: If your healthcare company isn’t getting leads from ChatGPT and Google AI Overviews, it’s probably because your content isn’t optimized for AI search. Tely AI runs keywords and questions research, generates and publishes GEO content, and captures new leads – all on autopilot. Create your first article on us to start filling your pipeline with patients and partners from today’s lead sources.
- Withings and Babyscripts Team Up on Maternal Health: Babyscripts is teaming up with Withings Health Solutions to tackle the leading cause of maternal mortality in the U.S. – hypertensive disorders of pregnancy, including preeclampsia. Learn how remote patient monitoring with BPM Pro 2 is helping Babyscripts keep mothers safe through personalized support when they need it most.
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